Tilganga Institute of Ophthalmology (TIO) or Tilganga Eye Center for avoidance and control of visual impairment program in Nepal is the executing body of the Nepal Eye Program, a non-benefit, group based, non-government association. The present office was opened in 1994. With an intend to go about as a model for treatment research and preparing, autonomous of, however in co-operation with all other eye care focuses and associations in Nepal, the momentum TIO office was opened in 1994.The uvea (Lat. uva, grape), likewise called the uveal layer, uveal coat, uveal tract, or vascular tunic, is the pigmented center of the three concentric layers that make up an eye. The name is potentially a reference to its rosy blue or verging on dark shading, wrinkled appearance and grape-like size and shape when stripped in place from a cadaveric eye.Its utilization as a specialized term in life systems and ophthalmology is moderately modern.Glaucoma is a gathering of eye sicknesses which bring about harm to the optic nerve and vision loss. The most well-known sort is open-point glaucoma with less basic sorts including shut edge glaucoma and typical strain glaucoma. Open-edge glaucoma grows gradually after some time and there is no agony. Side vision may start to diminish took after by focal vision bringing about visual impairment if not treated. Closed-edge glaucoma can introduce step by step or suddenly. The sudden presentation may include extreme eye torment, obscured vision, mid-widened understudy, redness of the eye, and nausea. Vision misfortune from glaucoma, once it has happened, is permanent.Hazard component for glaucoma incorporate expanded weight in the eye, a family history of the condition, headaches, hypertension, and obesity. For eye weights an estimation of more prominent than 21 mmHg or 2.8 kPa is regularly utilized with higher weights prompting a more noteworthy risk. However, some may have high eye weight for quite a long time and never create damage.Conversely, optic nerve harm may happen with typical weight, known as expected pressure glaucoma.The instrument of open-point glaucoma is accepted to be moderate way out of fluid amusingness through the trabecular meshwork while in shut edge glaucoma the iris hinders the trabecular meshwork.Diagnosis is by a widened eye exam. Often the optic nerve demonstrates an element known as cupping.On the off chance that treated early it is conceivable to moderate or stop the movement of malady with drug, laser treatment, or surgery.The objective of these medicines is to abatement eye weight. Various diverse classes of glaucoma solution are accessible. Laser medications might be powerful in both open-point and shut edge glaucoma. Various sorts of glaucoma surgeries might be utilized as a part of individuals who don't react adequately to other measures. Treatment of shut edge glaucoma is a medicinal emergency.